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Transport of Bupropion and its Metabolites by the Model CHO and HEK293 Cell Lines

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Background: Bupropion (BUP) is widely used as an antidepressant and smoking cessation aid. There are three major pharmacologically active metabolites of BUP, Erythrohydrobupropion (EB), Hydroxybupropion (OHB) and Threohydrobuprop... ...