Disruption of palmitate-mediated localization; a shared pathway of force and anesthetic activation of TREK-1 channels
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TWIK related K+ channel (TREK-1) is a mechano- and anesthetic sensitive channel that when activated attenuates pain and causes anesthesia. Recently the enzyme phospholipase D2 (PLD2) was shown to bind to the channel and generate a local high concentration of p... ...
