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Identifying Anti-prion Chemical Compounds Using a Newly Established Yeast High-Throughput Screening System

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Prion-like protein aggregation underlies the pathology of a group of fatal neurodegenerative diseases in humans, including Alzheimer's disease (AD), Parkinson's disease, amyotrophic lateral sclerosis, and transmissible spongiform encephalopathy. At present, fe... ...