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PKCε regulates Rho GTPases and actin cytoskeleton reorganization in non-small cell lung cancer cells

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Oncogenic protein kinase C epsilon (PKCε) promotes the formation of membrane ruffles and motility in non-small cell lung cancer (NSCLC) cells. We found that PKCε is down-regulated when NSCLC cells undergo epithelial-to-mesenchymal transition (EMT) in respons... ...