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Ubiquilin 2 modulates ALS/FTD-linked FUS-RNA complex dynamics and stress granule formation

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The ubiquitin-like protein ubiquilin 2 (UBQLN2) has been genetically and pathologically linked to the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), but its normal cellular functions are not well understood. I... ...