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Sphingolipids modulate docking, Ca2+ sensitivity and membrane fusion of native cortical vesicles

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Docking, priming, and membrane fusion of secretory vesicles (i.e. regulated exocytosis) requires lipids and proteins. Sphingolipids, in particular, sphingosine and sphingosine-1-phosphate, have been implicated in the modulation of exocytosis. However, the spec... ...