First-in-human study of the anti-HB-EGF antibody U3-1565 in subjects with advanced solid tumors
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U3-1565 is a monoclonal antibody directed against heparin-binding epidermal growth factor-like growth factor (HB-EGF), which mediates angiogenesis via induction of vascular endothelial growth factor (VEGF-A). This first-in-human study characterized the safety,... ...
