Diversity synthesis of tetrahydroprotoberberines glycosides by combined chemical and microbial catalysis
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The present study was designed to construct the structurally diverse library of tetrahydroprotoberberines (THPBs) by combining the methods of chemical nonselective demethylation and microbial glycosylation. HPLC-MS/MS analyses tentatively identified 12 de-meth... ...