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In vivo characterization of CYP2D6*12, *29 and *84 using dextromethorphan as a probe drug: a case report

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CYP2D6*84 was first described in a Black South African subject, however, its function remains unknown. Astrolabe, a probabilistic scoring tool developed in our laboratory to call genotypes from whole genome sequence, identified CYP2D6*84 in a trio. The father ... ...