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The identification of protein domains that mediate functional interactions between Rab-GTPases and RabGAPs using 3D protein modeling

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Currently, time-consuming serial in vitro experimentation involving immunocytochemistry or radiolabeled materials is required to identify which of the numerous Rab-GTPases (Rab) and Rab-GTPase activating proteins (RabGAP) are capable of functional interactions... ...