Biophysical characterization and modeling of human Ecdysoneless (ECD) protein supports a scaffolding function
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The human homolog of Drosophila ecdysoneless protein (ECD) is a p53 binding protein that stabilizes and enhances p53 functions. Homozygous deletion of mouse Ecd is early embryonic lethal and Ecd deletion delays G1-S cell cycle progression. Importantly, ECD dir... ...
