Identification of a novel RASD1 somatic mutation in a USP8-mutated corticotroph adenoma
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Cushing's disease (CD) is caused by pituitary corticotroph adenomas that secrete excess adrenocorticotropic hormone (ACTH). In these tumors, somatic mutations in the gene USP8 have been identified as recurrent and pathogenic and are the sole known molecular dr... ...
