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Sequencing the CYP2D6 gene: from variant allele discovery to clinical pharmacogenetic testing

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CYP2D6 is one of the most studied enzymes in the field of pharmacogenetics. The CYP2D6 gene is highly polymorphic with over 100 catalogued star (*) alleles, and clinical CYP2D6 testing is increasingly accessible and supported by practice guidelines. However, t... ...