Distance constraints on activation of TRPV4 channels by AKAP150-bound PKCα in arterial myocytes
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TRPV4 (transient receptor potential vanilloid 4) channels are Ca2+-permeable channels that play a key role in regulating vascular tone. In arterial myocytes, opening of TRPV4 channels creates local increases in Ca2+ influx, detectable optically as "TRPV4 spark... ...
