Differential effect of the overexpression of Rad2/XPG family endonucleases on genome integrity in yeast and human cells
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Eukaryotic cells possess several DNA endonucleases that are necessary to complete different steps in DNA metabolism. Rad2/XPG and Rad27/FEN1 belong to a group of evolutionary conserved proteins that constitute the Rad2 family. Given the important roles carried... ...