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Intestinal surfactant permeation enhancers and their interaction with enterocyte cell membranes in a mucosal explant system

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Intestinal permeation enhancers (PEs) are agents aimed to improve oral delivery of therapeutic drugs with poor bioavailability. The main permeability barrier for oral delivery is the intestinal epithelium, and PEs act to increase the paracellular and/or transc... ...