Reduced gene expression of sirtuins and active AMPK levels in children and adolescents with obesity and insulin resistance
{{output}}
Background: Sirtuins, including SIRT1 and SIRT2, are longevity-associated deacetylase enzymes that modulate metabolic homeostasis in response to the cellular energy state. Adenosine monophosphate activated protein kinase (AMPK) a... ...
