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Mechanistic insight into the assembly of the HerA-NurA helicase-nuclease DNA end resection complex

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The HerA-NurA helicase-nuclease complex cooperates with Mre11 and Rad50 to coordinate the repair of double-stranded DNA breaks. Little is known, however, about the assembly mechanism and activation of the HerA-NurA. By combining hybrid mass spectrometry with c... ...