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Effect of miR-204&211 and RUNX2 control on the fate of human mesenchymal stromal cells

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MiR-204 and 211 enforced expression in murine mesenchymal stromal cells (MSCs) has been shown to induce adipogenesis and impair osteogenesis, through RUNX2 down-modulation. This mechanism has been suggested to play a role in osteoporosis associated with obesit... ...