CISH promoter polymorphism effects on T cell cytokine receptor signaling and type 1 diabetes susceptibility
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Background: Impaired regulatory T cell immunity plays a central role in the development of type 1 diabetes (T1D). Interleukin-2 receptor (IL-2R) signaling is essential for regulatory T cells (TREG), and cytokine-inducible SH2-con... ...
