Shedding new light on RhoA signalling as a drug target in vivo using a novel RhoA-FRET biosensor mouse
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The small GTPase RhoA is a master regulator of signalling in cell-extracellular matrix interactions. RhoA signalling is critical to many cellular processes including migration, mechanotransduction, and is often disrupted in carcinogenesis. Investigating RhoA a... ...
