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Site-specific derivatization of human interferon β-1a at lysine residues using microbial transglutaminase

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Microbial transglutaminase (TGase) has been successfully used to produce site-specific protein conjugates derivatized at the level of glutamine (Gln) or lysine (Lys) residues with diverse applications. Here, we study the drug human interferon β-1a (IFN) as a ... ...