The effect of different divalent cations on the kinetics and fidelity of Bacillus stearothermophilus DNA polymerase
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Although Mg2+ is the metal ion that functions as the cofactor for DNA polymerases (DNA pols) in vivo, Mn2+ can also serve in this capacity but it reduces base discrimination. Metal ions aside from Mg2+ or Mn2+ can act as cofactors for some DNA pols but not for... ...
