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[Effect of long-term treatment of Wuzhi tablet on the expression and activity of cytochrome P450 3A in rats]

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The study aims to evaluate the effect of long-term pretreatment of the rat with Wuzhi tablet(WZ) on hepatic and intestinal CYP3A mRNA and protein expression and activity. Male Sprague-Dawley rats were orally administered of midazolam (2 mg·kg-1) with or without... ...