[GGI as a gene carrier delivering MDR1 siRNA to A549/DDP cells for reversal of multidrug resistance]
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This study was designed to reverse multidrug resistance of lung cancer cells by downregulating MDR1 genes through RNA interference (RNAi) technology. A novel biodegradable cationic polymer (PEG- b- PLG-g-PEIs, GGI) was synthesized and characterized by 1H NMR. ... ...
