Characterization of the relationship between dose and blood eosinophil response following subcutaneous administration of mepolizumab
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Objective: Mepolizumab is a humanized IgG1 monoclonal antibody that blocks human IL-5 from binding to the IL-5 receptor, which is mainly expressed on eosinophils. Eosinophils are key cells in the inflammatory cascade of various d... ...
