p21(WAF1/CIP1) Expression is Differentially Regulated by Metformin and Rapamycin
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The mammalian target of rapamycin (mTOR) pathway plays an important role in the development of diabetic nephropathy and other age-related diseases. One of the features of DN is the elevated expression of p21(WAF1/CIP1). However, the importance of the mTOR sign... ...
