Clinical Pharmacology of Phenobarbital in Neonates: Effects, Metabolism and Pharmacokinetics
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Phenobarbital is an effective and safe anticonvulsant drug introduced in clinical use in 1904. Its mechanism of action is the synaptic inhibition through an action on GABAA. The loading dose of phenobarbital is 20 mg/kg intravenously and the maintenance dose i... ...
