The MATE1 rs2289669 polymorphism affects the renal clearance of metformin following ranitidine treatment
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Purpose: Human multidrug and toxin extrusion member 1 (MATE1, SLC47A1) and Organic Cation Transporter 2 (OCT2, SLC22A2) play important roles in the renal elimination of various pharmacologic agents, including the anti-diabetic dr... ...
