Blockade of P-Glycoprotein Decreased the Disposition of Phenformin and Increased Plasma Lactate Level
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This study aimed to investigate the in vivo relevance of P-glycoprotein (P-gp) in the pharmacokinetics and adverse effect of phenformin. To investigate the involvement of P-gp in the transport of phenformin, a bi-directional transport of phenformin was carried... ...
