The PBAF chromatin remodeling complex represses transcription and promotes rapid repair at DNA double-strand breaks
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Transcription in the vicinity of DNA double-strand breaks (DSBs) is suppressed via a process involving ataxia telangiectasia mutated protein (ATM) and H2AK119 ubiquitylation.(1) We discuss recent findings that components of the Polybromo and Brahma-related gen... ...
