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[Inhibition of prostaglandins synthesis in the inflamed site results in opioid-mediated hypoalgesia in rats]

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This study was designed to investigate the contribution of prostaglandins to the maintenance of inflammatory pain. Inflammation was induced by intraplantar (i.pl.) injection of carrageenan in right hindpaw in rats. Indomethacin (non-selective COX inhibitor) wa... ...