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Collaborative study for the validation of an improved HPLC assay for recombinant IFN-alfa-2

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The current European Pharmacopoeia (Ph. Eur.) texts for Interferon (IFN)-alfa-2 include a nonspecific photometric protein assay using albumin as calibrator and a highly variable cell-based assay for the potency determination of the protective effects. A reques... ...