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Oxidative medicine and cellular longevity. 2016:2016:3912515. doi: 10.1155/2016/3912515 Q20.02025

Inhibition of Glucose-6-Phosphate Dehydrogenase Could Enhance 1,4-Benzoquinone-Induced Oxidative Damage in K562 Cells

葡萄糖六磷酸脱氢酶抑制能增强1,4苯醌诱导的K562细胞氧化损伤 翻译改进

Juan Zhang  1, Meng Cao  1, Wenwen Yang  1, Fengmei Sun  1, Cheng Xu  1, Lihong Yin  1, Yuepu Pu  1

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  • 1 Key Laboratory of Environmental Medicine Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China.
  • DOI: 10.1155/2016/3912515 PMID: 27656260

    摘要 Ai翻译

    Benzene is a chemical contaminant widespread in industrial and living environments. The oxidative metabolites of benzene induce toxicity involving oxidative damage. Protecting cells and cell membranes from oxidative damage, glucose-6-phosphate dehydrogenase (G6PD) maintains the reduced state of glutathione (GSH). This study aims to investigate whether the downregulation of G6PD in K562 cell line can influence the oxidative toxicity induced by 1,4-benzoquin... ...点击完成人机验证后继续浏览
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    期刊名:Oxidative medicine and cellular longevity

    缩写:OXID MED CELL LONGEV

    ISSN:1942-0900

    e-ISSN:1942-0994

    IF/分区:0.0/Q2

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    Inhibition of Glucose-6-Phosphate Dehydrogenase Could Enhance 1,4-Benzoquinone-Induced Oxidative Damage in K562 Cells