Autophagy Activation by Transcription Factor EB (TFEB) in Striatum of HDQ175/Q7 Mice
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Background: Mutant huntingtin (mHTT) is encoded by the Huntington's disease (HD) gene and its accumulation in the brain contributes to HD pathogenesis. Reducing mHTT levels through activation of the autophagosome-lysosomal pathwa... ...
