Regulation of Siglec-8-induced intracellular reactive oxygen species production and eosinophil cell death by Src family kinases
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Rationale: Siglec-8 is a surface receptor predominantly expressed on human eosinophils where its ligation induces reactive oxygen species (ROS) formation and cell death. Since Siglec-8 has intracellular tyrosine-based motifs, we ... ...
