Substituted indole Mcl-1 inhibitors: a patent evaluation (WO2015148854A1)
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The myeloid cell leukemia 1 (Mcl-1) protein, an anti-apoptotic member of Bcl-2 family, plays a critical role in the development and maintenance of many cancers and is listed in the 'top ten' pathological factors across the diversity of human cancers. The paten... ...