Trileucine residues in a ligand-CPP-based siRNA delivery platform improve endosomal escape of siRNA
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siRNA entrapment within endosomes is a significant problem encountered with siRNA delivery platforms that co-opt receptor-mediated entry pathways. Attachment of a cell-penetrating peptide (CPP), such as nona-arginine (9R) to a cell receptor-binding ligand like... ...
