An updated patent review: xanthine oxidase inhibitors for the treatment of hyperuricemia and gout (2011-2015)
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Xanthine oxidase (XO) is a versatile molybdoflavoprotein, widely distributed, occurring in milk, kidney, lung, heart, and vascular endothelium. Catalysis by XO to produce uric acid and reactive oxygen species leads to many diseases. Anti hyperuricemic therapy ... ...