Recent advances in acetylcholinesterase Inhibitors and Reactivators: an update on the patent literature (2012-2015)
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Acetylcholinesterase (AChE) is the major enzyme that hydrolyzes acetylcholine, a key neurotransmitter for synaptic transmission, into acetic acid and choline. Mild inhibition of AChE has been shown to have therapeutic relevance in Alzheimer's disease (AD), mya... ...
