Acute myeloid leukemia with t(7;21)(p22;q22) and 5q deletion: a case report and literature review
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The gene RUNX1 at chromosome 21q22 encodes the alpha subunit of Core binding factor (CBF), a heterodimeric transcription factor involved in the development of normal hematopoiesis. Translocations of RUNX1 are seen in several types of leukemia with at least 21 ... ...
