Are T-LGL Leukemia and NK-Chronic Lymphoproliferative Disorder really two distinct diseases?
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Mature Large Granular lymphocytes (LGL) disorders include a spectrum of conditions, ranging from polyclonal to clonal indolent and/or overt leukemic LGL proliferations. Most cases are represented by clonal expansions of TCRα/β+ LGL displaying a CD8+ phenotyp... ...