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8-pCPT, an Epac activator, impairs conditioned place preference based on nucleus accumbens amphetamine in rats

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Objectives: Dopamine receptor-mediated 3',5'-cyclic adenosine monophosphate (cAMP)-dependent intracellular signalling is important for reward-related learning. cAMP activates cAMP-dependent protein kinase (PKA) and exchange prote... ...