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Inducible tyrosine kinase inhibitors: a review of the patent literature (2010 - 2013)

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Introduction: The non-receptor tyrosine kinase, inducible tyrosine kinase (Itk), plays an important role in thymus(T)-cell signalling and the production of pro-inflammatory cytokines. Itk, and the other Tec family members, Rlk an... ...