Equol is neuroprotective during focal cerebral ischemia and reperfusion that involves p-Src and gp91(phox)
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Both of gp91(phox) (an isoform of nicotinamide adenine dinucleotide phosphate reduced oxidases) and Src (a nonreceptor protein tyrosine kinase) are abundantly expressed in the brain and play a prominent role in mediating ischemic alteration in neurons. The inh... ...
