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PloS one. 2014 Sep 15;9(9):e107191. doi: 10.1371/journal.pone.0107191 Q22.62025

Serum 8,12-iso-iPF2α-VI isoprostane marker of oxidative damage and cognition deficits in children with konzo

儿童konzo患者血清中的8,12-异构-iPF2α-VI异丙酚标志物与氧化损伤和认知缺陷的关系 翻译改进

Bumoko G Makila-Mabe  1, Kambale J Kikandau  2, Thérèse M Sombo  1, Daniel L Okitundu  1, Jean-Claude Mwanza  3, Michael J Boivin  4, Mumba D Ngoyi  5, Jean-Jacques T Muyembe  5, Jean-Pierre Banea  6, Gerard R Boss  7, Desiré Tshala-Katumbay  8

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  • 1 Department of Neurology, University of Kinshasa, Kinshasa, Congo-Kinshasa.
  • 2 Department of Biomedical Sciences, University of Kinshasa, Kinshasa, Congo-Kinshasa.
  • 3 Department of Ophthalmology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
  • 4 Department of Psychiatry and Neurology/Ophthalmology, Michigan State University, East Lansing, Michigan, United States of America.
  • 5 Department of Tropical Medicine, University of Kinshasa, Kinshasa, Congo-Kinshasa; Department of Parasitology, Institut National de Recherches Biomédicales, Kinshasa, Congo-Kinshasa.
  • 6 Department of Nutrition, School of Public Health & National Nutrition Program, Ministry of Health, Kinshasa, Congo-Kinshasa.
  • 7 Department of Medicine, University of California San Diego, La Jolla, California, United States of America.
  • 8 Department of Neurology, University of Kinshasa, Kinshasa, Congo-Kinshasa; Department of Neurology, Oregon Health & Science University, Portland, Oregon, United States of America; Oregon Institute of Occupational Health Sciences, Oregon Health & Science University, Portland, Oregon, United States of America.
  • DOI: 10.1371/journal.pone.0107191 PMID: 25222616

    摘要 Ai翻译

    We sought to determine whether motor and cognitive deficits associated with cassava (food) cyanogenic poisoning were associated with high concentrations of F2-isoprostanes, well-established indicators of oxidative damage. Concentrations of serum F2-isoprostanes were quantified by LC-MS/MS and anchored to measures of motor proficiency and cognitive performance, which were respectively assessed through BOT-2 (Bruininks/Oseretsky Test, 2nd Edition) and KABC-I... ...点击完成人机验证后继续浏览
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    期刊名:Plos one

    缩写:PLOS ONE

    ISSN:1932-6203

    e-ISSN:1932-6203

    IF/分区:2.6/Q2

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    Serum 8,12-iso-iPF2α-VI isoprostane marker of oxidative damage and cognition deficits in children with konzo