Ionizing radiation-induced XRCC4 phosphorylation is mediated through ATM in addition to DNA-PK
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XRCC4 (X-ray cross-complementation group 4) is a protein associated with DNA ligase IV, which is thought to join two DNA ends at the final step of DNA double-strand break repair through non-homologous end-joining. It has been shown that, in response to irradia... ...