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Effects of BIO on proliferation and chondrogenic differentiation of mouse marrow-derived mesenchymal stem cells

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In vitro expansion of mesenchymal stem cell (MSCs) into large number is necessary for their application in cell-based treatment of articular cartilage defects. On the other hand, some studies have indicated that BIO (6-Bromoindirubin-3-Oxime) possesses mitogen... ...