Caspase-mediated apoptosis in the cochleae contributes to the early onset of hearing loss in A/J mice
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A/J and C57BL/6 J (B6) mice share a mutation in Cdh23 (ahl allele) and are characterized by age-related hearing loss. However, hearing loss occurs much earlier in A/J mice at about four weeks of age. Recent study has revealed that a mutation in citrate synthas... ...
