HMGB1 expression and muscle regeneration in idiopathic inflammatory myopathies and degenerative joint diseases
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The High-Mobility Group Box 1 protein (HMGB1) is a known nuclear protein which may be released from the nucleus into the cytoplasm and the extracellular space. It is believed that the mobilized HMGB1 plays role in the autoimmune processes as an alarmin, stimul... ...